Brain-mapping projects using the common marmoset. (April 2015)

• Record Type: Journal Article
• Authors: Okano, Hideyuki; Mitra, Partha
• Is Part Of: Neuroscience research. Volume 93(2015:Apr.)
• Page Start: 3
• Page End: 7
• Publication Date: 2015-04
• Subjects: Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) -- Diffusion tensor imaging (DTI) -- Brain-wide connectivity maps -- Macroscopic structural mapping -- Mesoscopic structural mapping -- Microscopic structural mapping; Neurosciences -- Research -- Periodicals; Neurosciences -- Research -- Japan -- Periodicals; Neurology -- Periodicals; Neurosciences -- Periodicals; Neurosciences -- Recherche -- Périodiques; Neurosciences -- Recherche -- Japon -- Périodiques; Neurosciences -- Research; Japan; Periodicals; 612.8
• DOI: 10.1016/j.neures.2014.08.014
• Languages: English
• ISSNs: 0168-0102

Abstract

Highlights: The Japanese brain-mapping project (Brain/MINDS) was launched in 2014. Structural and functional brain mapping of the common marmoset plays a crucial role in Brain/MINDS. Cooperative interaction among the BRAIN Initiative, the HBP, and Brain/MINDS will be necessary to achieve the goals of the projects. Abstract: Globally, there is an increasing interest in brain-mapping projects, including the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative project in the USA, the Human Brain Project (HBP) in Europe, and the Brain Mapping by Integrated Neurotechnologies for Disease Studies (Brain/MINDS) project in Japan. These projects aim to map the structure and function of neuronal circuits to ultimately understand the vast complexity of the human brain. Brain/MINDS is focused on structural and functional mapping of the common marmoset ( Callithrix jacchus ) brain. This non-human primate has numerous advantages for brain mapping, including a well-developed frontal cortex and a compact brain size, as well as the availability of transgenic technologies. In the present review article, we discuss strategies for structural and functional mapping of the marmoset brain and the relation of the common marmoset to other animals models.