Diketopyrrolopyrrole-based novel ratiometric fluorescent chemodosimeter for Hg2+ detection in aqueous solution and in living cells. (November 2016)

• Record Type: Journal Article
• Authors: Bi, Shiming; Zhang, Guanjun; Wu, Yue; Wu, Shengying; Wang, Limin
• Is Part Of: Dyes and pigments. Volume 134(2016)
• Page Start: 586
• Page End: 592
• Publication Date: 2016-11
• Subjects: Diketopyrrolopyrrole -- Fluorescent chemodosimeter -- Ratiometric -- Hg2+ -- Aqueous solutions; Dyes and dyeing -- Periodicals; Pigments -- Periodicals; 667.2
• DOI: 10.1016/j.dyepig.2016.08.001
• Languages: English
• ISSNs: 0143-7208

Abstract

Abstract: A new ratiometric fluorescent chemodosimeter based on the skeleton of diketopyrrolopyrrole was rationally designed and synthesized, which presented high sensitivity, selectivity for Hg 2+ over other metal ions in aqueous solution leading to further applications of cell imaging. Red shift of chemodosimeter on absorption and fluorescence spectra upon Hg 2+ binding was observed, which changed linearly with increase of Hg 2+ . This phenomenon was a typical deprotection process of acetal groups which increased the conjunction of DPP core that were confirmed by DFT. Graphical abstract: Highlights: A new Diketopyrrolopyrrole-based ratiometric probe were designed and synthesized. The recognition mechanism had been fully proved (deprotection of acetal groups). It presented high sensitivity, selectivity for Hg 2+ over other metal ions. It works perfectly in aqueous solution. It has further applications of Hg 2+ detection in living cells.