Isolation and cytotoxic investigation of new carbazole alkaloids from Murraya koenigii (Linn.) Spreng. Issue 23 (10th June 2015)
- Record Type:
- Journal Article
- Title:
- Isolation and cytotoxic investigation of new carbazole alkaloids from Murraya koenigii (Linn.) Spreng. Issue 23 (10th June 2015)
- Main Title:
- Isolation and cytotoxic investigation of new carbazole alkaloids from Murraya koenigii (Linn.) Spreng
- Authors:
- Tan, Siow-Ping
Ali, Abdul Manaf
Nafiah, Mohd Azlan
Awang, Khalijah
Ahmad, Kartini - Abstract:
- Abstract: Six new carbazole alkaloids, murrastanine-A (1 ), murrastinine-A, -B, -C (2 –4 ), murrayatanine-A (5 ) and bismahanimboline (6 ), were isolated from the bark and leaves of Murraya koenigii (Linn.) Spreng along with 24 known carbazole alkaloids. The structure of these compounds were elucidated by extensive spectroscopic analysis. Murrastinine-C (4 ) and murrayatanine-A (5 ) exhibited cytotoxic activity against HL-60 and HeLa (CD50 <20 μg/mL) via MTT assay. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 71:Issue 23(2015)
- Journal:
- Tetrahedron
- Issue:
- Volume 71:Issue 23(2015)
- Issue Display:
- Volume 71, Issue 23 (2015)
- Year:
- 2015
- Volume:
- 71
- Issue:
- 23
- Issue Sort Value:
- 2015-0071-0023-0000
- Page Start:
- 3946
- Page End:
- 3953
- Publication Date:
- 2015-06-10
- Subjects:
- Carbazoles -- Cytotoxicity -- Murraya koenigii -- MTT assay -- Rutaceae
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2015.04.037 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7355.xml