(+) RNA virus replication compartments: a safe home for (most) viral replication. (August 2016) - Shulla, Ana
Highlights: (+) RNA virus replication compartments form two structural classes. Both classes of replication compartments use cellular membrane curvature proteins. Both classes of replication compartments manipulate de novo lipid synthesis. Some double membrane vesicles use cellular lipid kinases and transfer proteins. Limited transient replication may occur before replication compartment formation. Abstract : This review describes recent advances in our understanding of the mechanisms by which (+) RNA viruses establish their replication niche.