Immune reconstitution inflammatory syndrome, human herpesvirus 8 viremia, and HIV-associated multicentric Castleman disease. (July 2016)

• Record Type: Journal Article
• Authors: Siegel, Marc O.; Ghafouri, Sanaz; Ajmera, Ravi; Simon, Gary L.
• Is Part Of: International journal of infectious diseases. Volume 48(2016:Jul.)
• Page Start: 49
• Page End: 51
• Publication Date: 2016-07
• Subjects: Human herpesvirus-8 -- Multicentric Castleman's disease -- Human immunodeficiency virus -- Immune reconstitution inflammatory syndrome; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Electronic journals; 616.9
• DOI: 10.1016/j.ijid.2016.05.005
• Languages: English
• ISSNs: 1201-9712

Abstract

Summary: Kaposi's sarcoma and multicentric Castleman Disease are HIV-related disease processes that are associated with human herpesvirus 8 (HHV-8) infection. The development of multicentric Castleman disease can often be a manifestation of the immune reconstitution inflammatory syndrome phenomenon and is associated with markedly elevated levels of HHV-8 viremia, as illustrated by this case.