Computing Substrate Selectivity in a Peptide Transporter. Issue 2 (18th February 2016)

• Record Type: Journal Article
• Authors: Colas, Claire; Smith, David E.; Schlessinger, Avner
• Is Part Of: Cell chemical biology. Volume 23:Issue 2(2016)
• Page Start: 211
• Page End: 213
• Publication Date: 2016-02-18
• Subjects: Biochemistry -- Periodicals; 572.05
• DOI: 10.1016/j.chembiol.2016.02.001
• Languages: English
• ISSNs: 2451-9456

Abstract

Abstract : The human proton-coupled peptide transporter 1 (PepT1) is responsible for the absorption of di- and tri-peptides from the diet and peptide-like drugs. In this issue of Cell Chemical Biology, Samsudin et al. (2016) use an integrated computational and experimental approach to provide new insights into understanding substrate selectivity of PepTSt, a prokaryotic homolog of the human PepT1. Abstract : The human proton-coupled peptide transporter 1 (PepT1) is responsible for the absorption of di- and tri-peptides from the diet and peptide-like drugs. In this issue of Cell Chemical Biology, Samsudin et al. (2016) use an integrated computational and experimental approach to provide new insights into understanding substrate selectivity of PepTSt, a prokaryotic homolog of the human PepT1.