Outcomes of fertility-sparing surgery among young women with FIGO stage I clear cell carcinoma of the ovary. Issue 1 (July 2016)

• Record Type: Journal Article
• Authors: Park, Jeong-Yeol; Suh, Dae-Shik; Kim, Jong-Hyeok; Kim, Yong-Man; Kim, Young-Tak; Nam, Joo-Hyun
• Is Part Of: International journal of gynaecology and obstetrics. Volume 134:Issue 1(2016:Jul.)
• Page Start: 49
• Page End: 52
• Publication Date: 2016-07
• Subjects: Clear cell carcinoma -- Early stage -- Fertility-sparing surgery -- Ovary -- Ovarian cancer; Gynecology -- Periodicals; Obstetrics -- Periodicals; Electronic journals; 618
• DOI: 10.1016/j.ijgo.2015.10.022
• Languages: English
• ISSNs: 0020-7292

Abstract

Abstract: Objectives: To evaluate the outcome of fertility-sparing surgery among young women with early-stage clear cell carcinoma of the ovary. Methods: In a retrospective study, data were reviewed for patients aged 45 years or younger who had FIGO stage I clear cell carcinoma of the ovary and had attended one institution in South Korea between December 1999 and December 2009. Outcomes were compared between women undergoing fertility-sparing surgery, defined as preservation of the uterus and at least one adnexa, and those undergoing radical surgery. Results: Overall, 47 patients were included (22 underwent fertility-sparing surgery, 25 radical surgery). After a median follow-up of 72 months (range 8–175), 5 (23%) patients who underwent fertility-sparing surgery and 5 (20%) in the radical surgery group had recurrent disease ( P = 0.820). The mean time to recurrence was 19 months after fertility-sparing surgery versus 20 months after radical surgery ( P = 0.935). The anatomical location of recurrence did not differ. There was no difference in 5-year disease-free survival (77% vs 84%; P = 0.849) or 5-year overall survival (91% vs 88%; P = 0.480). Conclusion: Fertility-sparing surgery was found to be a safe alternative for young women with FIGO stage I clear cell carcinoma of the ovary who wish to preserve fertility.