Detection of crossing vessels in pediatric ureteropelvic junction obstruction: Clinical patterns and imaging findings. Issue 4 (August 2015)

• Record Type: Journal Article
• Authors: Weiss, Dana A.; Kadakia, Sagar; Kurzweil, Rebecca; Srinivasan, Arun K.; Darge, Kassa; Shukla, Aseem R.
• Is Part Of: Journal of pediatric urology. Volume 11:Issue 4(2015)
• Page Start: 173.e1
• Page End: 173.e5
• Publication Date: 2015-08
• Subjects: Ureteropelvic junction obstruction -- Crossing renal vessel -- Antenatal hydronephrosis -- Functional magnetic resonance urography; Pediatric urology -- Periodicals; Urologic Diseases -- Periodicals; Urogenital Diseases -- Periodicals; Urologic Surgical Procedures -- Periodicals; Child; Infant; Urologie pédiatrique -- Périodiques; Appareil urinaire -- Maladies -- Périodiques; Pédiatrie; Urologie; Pediatric urology; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); Electronic journals; Periodicals; Electronic journals; 618.926
• DOI: 10.1016/j.jpurol.2015.04.017
• Languages: English
• ISSNs: 1477-5131

Abstract

Summary: Background: Pediatric ureteropelvic junction obstruction (UPJO) is caused by congenital intrinsic narrowing and/or a lower pole-crossing renal artery. When a crossing renal vessel (CRV) is missed at the time of pyeloplasty, a redo-pyeloplasty is often required. Objectives: The aims were to analyze clinical predictors for the presence of a CRV in UPJO and the utility of functional magnetic resonance urography (fMRU) in preoperative identification of a crossing vessel. Methods: Using an Institutional Review Board approved registry database, we identified 166 patients from July of 2007 until January of 2014 who had undergone open, laparoscopic, or robotic assisted laparoscopic pyeloplasty at our institution. We abstracted data including age at surgery, preoperative symptoms, preoperative imaging findings, and whether or not a CRV was identified intraoperatively. Statistical analysis was performed on SPSS using the Mann–Whitney U test. Results: Of the 166 patients identified, 78 were found to have a CRV at the time of surgery and 88 did not. The surgical approach was distributed as 104 robotic assisted laparoscopic, 51 open, and 11 pure laparoscopic. On univariate analysis, older age at presentation and pain at presentation predicted the presence of a CRV; antenatal hydronephrosis was a negative predictor, though 20 of 68 (25.6%) infants diagnosed with UPJO antenatally did have a CRV. Subgroup analysis of patients undergoing preoperative MRU showed a sensitivity of 88.2% and specificity of 91.7% for the detection of CRVs. Discussion: This study confirmed the importance of looking for a crossing vessel in all cases, with the knowledge that increased age and pain at presentation were more likely to be associated with a crossing vessel. In addition, fMRU is a valuable source of information in the preoperative identification of the presence of a crossing vessel. The study has limitations including being retrospective in nature, and that the sensitivity of fMRU to identify CRVs was based on the read of an experienced uroradiologist who specializes in MRU, so may not correlate with the standard clinical read of an fMRU. Conclusion: This study confirms the need to maintain a high index of suspicion for the presence of a CRV when intervening in a clinically symptomatic older child, although 25% of infants with antenatally detected UPJO did have one too. Our subset analysis demonstrated that MRU is a reliable method of detecting crossing vessels. Figure (A) Normal bilateral renal arteries (arrows) on post-contrast T1-weighted fat-saturated scan. On the left side there is ureteropelvic junction obstruction and clearly the left renal artery enters into the kidney above the dilated renal pelvis. (B) Left crossing vessel detected on post-contrast T1-weighted fat-saturated scan (thin arrow) without additional signs of obstruction on fMRU (not shown) and, no crossing found intraoperatively. (C) A post-contrast T1-weighted fat-saturated scan demonstrating a right crossing vessel (arrow) arising as a branch from the main renal artery and wrapping around the dilated renal pelvis to enter the kidney at the ureteropelvic junction. (D) Obstruction of the proximal ureter is noted (arrow) on the non-contrast 3D T2-weighted fat-saturated scan. The obstructing right crossing vessel was identified intraoperatively. (E) Sensitivity and specificity of fMRU for identification of the presence of crossing renal vessels and for ureteral obstruction.