Resting extracellular signal-regulated protein kinase 1/2 expression following a continuum of chronic resistance exercise training paradigms. Issue 3 (2nd July 2016)

• Record Type: Journal Article
• Authors: Galpin, Andrew J.; Fry, Andrew C.; Nicoll, Justin X.; Moore, Christopher A.; Schilling, Brian K.; Thomason, Donald B.
• Is Part Of: Research in sports medicine. Volume 24:Issue 3(2016)
• Page Start: 298
• Page End: 303
• Publication Date: 2016-07-02
• Subjects: Skeletal muscle -- weightlifting -- powerlifting -- circuit training -- MAPK; Sports medicine -- Periodicals; Athletic Injuries -- Periodicals; Exercise -- Periodicals; Sports Medicine -- Periodicals; Médecine du sport -- Périodiques; 617.102705
• DOI: 10.1080/15438627.2016.1202825
• Languages: English
• ISSNs: 1543-8627

Abstract

ABSTRACT: Extracellular signal-regulated protein kinase 1/2 (ERK1/2) moderates skeletal muscle growth; however, chronic responses of this protein to unique resistance exercise (RE) paradigms are yet to be explored. The purpose of this investigation was to describe the long-term response of ERK1/2 following circuit weight training (CWT), recreationally weight training (WT), powerlifting (PL) and weightlifting (WL). Independent t -tests were used to determine differences in trained groups compared to sedentary controls. Total ERK1/2 content was lower in PL and WL compared to their controls ( p ≤ 0.05). Specific trained groups displayed large (WL: pERK/total-ERK; d = 1.25) and moderate (CWT: total ERK1/2; d = 0.54) effect sizes for altered kinase expression compared to controls. The results indicate ERK1/2 expression is down-regulated after chronic RE in well-trained weightlifters and powerlifters. Lower expression of this protein may be a method in which anabolism is tightly regulated after many years of high-intensity RE.