Extracorporeal membrane oxygenation for profound cardiogenic shock due to cocaine toxicity. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Grimm, Joshua C.; Balsara, Keki R.; Kemp, Clinton D.; Miller, Jared; Myers, Mollie; Schulman, Steven P.; Sciortino, Christopher M.
• Is Part Of: Journal of cardiology cases. Volume 11:Issue 1(2015:Jan.)
• Page Start: 28
• Page End: 31
• Publication Date: 2015-01
• Subjects: Extracorporeal membrane oxygenation -- Coronary artery vasospasm -- Cocaine toxicity; Cardiology -- Periodicals; Cardiovascular Diseases -- Case Reports; Cardiovascular Diseases -- Periodicals; Cardiology -- Case Reports; Cardiology -- Periodicals; Cardiology; Electronic journals; Periodicals; 616.12
• DOI: 10.1016/j.jccase.2014.09.005
• Languages: English
• ISSNs: 1878-5409

Abstract

Abstract: Cocaine toxicity can result in myocardial infarction from coronary vasospasm. The current treatment algorithm includes intravenous and/or intracoronary vasodilator administration with an expectantly quick resolution of symptoms and signs of ischemia. However, in situations in which myocardial injury persists, the optimal management is uncertain. We present a case in which extracorporeal membrane oxygenation effectively stabilized a patient with ongoing hemodynamic instability who experienced repeated episodes of myocardial injury and ventricular tachyarrhythmias due to cocaine toxicity. <Learning objective: In many urban settings, cocaine-induced angina is not uncommon. The pathogenesis of its manifestation includes coronary artery vasospasm and decreased left ventricular function. Treatment typically involves systemic vasodilators, such as nitrates and calcium channel blockers. However, in patients with substantial hemodynamic instability, these agents might result in a worsening of systemic perfusion. Accordingly, extracorporeal membrane oxygenation should be considered in such cases to promote myocardial recovery.>