Cationic rhodium(I)/BIPHEP complex-catalyzed cross-cyclotrimerization of silylacetylenes and unsymmetrical electron-deficient internal alkynes. Issue 34 (19th August 2015)

• Record Type: Journal Article
• Authors: Heya, Arisa; Namba, Tomoya; Hara, Jun; Shibata, Yu; Tanaka, Ken
• Is Part Of: Tetrahedron letters. Volume 56:Issue 34(2015)
• Page Start: 4938
• Page End: 4942
• Publication Date: 2015-08-19
• Subjects: Alkynes -- Alkynoates -- Cyclotrimerization -- Rhodium -- Silylacetylenes; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2015.06.096
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Abstract: It has been established that a cationic rhodium(I)/BIPHEP complex catalyzes the chemo- and regioselective intermolecular cross-cyclotrimerization of silylacetylenes with unsymmetrical electron-deficient internal alkynes. Chemoselectivity was highly dependent on steric bulk of the unsymmetrical electron-deficient internal alkynes used. Two molecules of sterically less demanding alkynoates and alkynone reacted with one molecule of the silylacetylene, on the contrary, one molecule of a sterically demanding alkynoate reacted with two molecules of the silylacetylene.