Overlapping self-expandable metallic stent for palliation of a long (>10 cm) malignant gastroduodenal obstruction. (May 2017)

• Record Type: Journal Article
• Authors: Tsauo, Jiaywei; Yoo, Moon-Won; Park, Jung-Hoon; Song, Ho-Young; Jun, Eun Jung; Cho, Young Chul; Kim, Guk Bae
• Is Part Of: Acta radiologica. Volume 58:Number 5(2017:May)
• Page Start: 565
• Page End: 572
• Publication Date: 2017-05
• Subjects: Gastric outlet obstruction -- pyloric stenosis -- prostheses and implants; Radiology, Medical -- Periodicals; Radiography, Medical -- Periodicals; Radiotherapy -- Periodicals; 616.0757
• DOI: 10.1177/0284185116664228
• Languages: English
• ISSNs: 0284-1851

Abstract

Background: Self-expandable metallic stent (SEMS) placement is a well-established palliative treatment approach for malignant gastroduodenal obstruction. In patients with a long (>10 cm) stricture, multiple stents placed in an overlapping fashion are often required. Purpose: To investigate the outcomes of overlapping SEMS placement for the palliative treatment of malignant gastroduodenal obstruction in patients with a long (>10 cm) stricture. Material and Methods: The medical records of 40 patients who underwent fluoroscopic overlapping SEMS placement for malignant gastroduodenal obstruction due to a long (>10 cm) stricture were reviewed. Results: The technical and clinical success rates were 100% and 65.0%, respectively. The mean length of the stricture was 17.0 ± 4.7 cm and the mean number of stents placed in each patient was 2.2 ± 0.5. Metastatic cancer (odds ratio [OR], 0.315; P = 0.018), Eastern Cooperative Oncology Group (ECOG) score ≥3 (OR, 0.018; P = 0.006), and carcinomatosis with ascites (OR, 0.025; P = 0.017) were independent predictors of poor clinical success. The rates of minor and major complications were 27.5% and 2.5%, respectively. The median stent patency and survival were 33 days (interquartile range [IQR], 19–60 days) and 35 days (IQR, 19–73 days), respectively. An ECOG score ≥3 was an independent predictor of a poor survival outcome (hazard ratio, 4.681; P < 0.001). Conclusion: Overlapping SEMS placement may be safe and effective for the palliative treatment of malignant gastroduodenal obstruction in patients with a long (>10 cm) stricture.