B(C6F5)3 catalyzed direct nucleophilic substitution of benzylic alcohols: an effective method of constructing C–O, C–S and C–C bonds from benzylic alcohols. Issue 54 (3rd September 2018)

• Record Type: Journal Article
• Authors: Meng, Shan-Shui; Wang, Qian; Huang, Gong-Bin; Lin, Li-Rong; Zhao, Jun-Ling; Chan, Albert S. C.
• Is Part Of: RSC advances. Volume 8:Issue 54(2018)
• Page Start: 30946
• Page End: 30949
• Publication Date: 2018-09-03
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c8ra05811c
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : An efficient and general method of nucleophilic substitution of benzylic alcohols catalyzed by non-metallic Lewis acid B(C6 F5 )3 was developed. Abstract : An efficient and general method of nucleophilic substitution of benzylic alcohols catalyzed by non-metallic Lewis acid B(C6 F5 )3 was developed. The reaction could be carried out under mild conditions and more than 35 examples of ethers, thioethers and triarylmethanes were constructed in high yields. Some bioactive organic molecules were synthesized directly using the methods.