A new generation electrochemical sensor based on Graphene nanosheets/Gold nanoparticles/Nafion nanocomposite for determination of Silodosin. (1st March 2015)

• Record Type: Journal Article
• Authors: Er, Engin; Çelikkan, Hüseyin; Erk, Nevin; Aksu, M.Levent
• Is Part Of: Electrochimica acta. Volume 157(2015)
• Page Start: 252
• Page End: 257
• Publication Date: 2015-03-01
• Subjects: Electrochemical sensor -- Graphene -- Chemical modified electrode -- Gold nanoparticle -- Silodosin; Electrochemistry -- Periodicals; Electrochemistry, Industrial -- Periodicals; 541.37
• DOI: 10.1016/j.electacta.2015.01.020
• Languages: English
• ISSNs: 0013-4686

Abstract

Graphical abstract: Abstract: It is the first time that a rapid, facile, highly sensitive and selective electrochemical sensor based on graphene nanosheets/gold nanoparticles/nafion nanocomposite modified electrode (GRP/AuNPs/NFN) was developed for the electro-oxidation and quantification of silodosin (SLD). The chemical formation of GRP/AuNPs nanocomposite was verified by x-ray diffraction (XRD), fourier transform infrared spectroscopy (FT-IR) and transmission electron spectroscopy (TEM). The electrochemical oxidation of SLD has been investigated at GRP/AuNPs/NFN by the use of adsorptive stripping differential pulse voltammetry (AdSDPV). The developed electrode exhibited excellent electrochemical activity towards the electrochemical oxidation of SLD. Under optimal conditions, GRP/AuNPs/NFN demonstrated a wide linearity ranging from 10–330 nM with a detection limit of 3.8 nM (S/N = 3). Therefore, the electrode developed can conveniently be used for the electroanalytical determination of SLD in pharmaceutical or biological samples.