UK guideline for the use of HIV Post-Exposure Prophylaxis Following Sexual Exposure, 2015. (August 2016)

• Record Type: Journal Article
• Authors: Cresswell, Fiona; Waters, Laura; Briggs, Eleanor; Fox, Julie; Harbottle, Justin; Hawkins, David; Murchie, Martin; Radcliffe, Keith; Rafferty, Paul; Rodger, Alison; Fisher, Martin
• Is Part Of: International journal of STD & AIDS. Volume 27:Number 9(2016:Sep.)
• Page Start: 713
• Page End: 738
• Publication Date: 2016-08
• Subjects: HIV -- AIDS -- Post-exposure prophylaxis (PEP) -- sexual exposure -- HIV prevention -- BASHH guidelines -- antiretroviral therapy; Sexually transmitted diseases -- Periodicals; AIDS (Disease) -- Periodicals; 616.951
• DOI: 10.1177/0956462416641813
• Languages: English
• ISSNs: 0956-4624

Abstract

We present the updated British Association for Sexual Health and HIV guidelines for HIV post-exposure prophylaxis following sexual exposure (PEPSE). This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of infection after a potential exposure, and provides recommendations on when PEPSE should and should not be considered. We also review which medications to use for PEPSE, provide a checklist for initial assessment, and make recommendations for monitoring individuals receiving PEPSE. Special scenarios, cost-effectiveness of PEPSE, and issues relating to service provision are also discussed. Throughout the document, the place of PEPSE within the broader context of other HIV prevention strategies is considered.