Bloodstream infections and antimicrobial sensitivity patterns in a tertiary care hospital of India. (October 2016)

• Record Type: Journal Article
• Authors: Vasudeva, Nikita; Nirwan, Prem Singh; Shrivastava, Preeti
• Is Part Of: Therapeutic advances in infectious disease. Volume 3:Number 5(2016:Oct.)
• Page Start: 119
• Page End: 127
• Publication Date: 2016-10
• Subjects: Blood Stream infections -- Antibiotic Sensitivity -- Antimicrobial resistance BACTEC; Communicable diseases -- Treatment -- Periodicals; Infection -- Treatment -- Periodicals; 616.905
• DOI: 10.1177/2049936116666983
• Languages: English
• ISSNs: 2049-9361

Abstract

Background: Invasion of the bloodstream by microorganisms constitutes one of the most serious situations in infectious disease. Microorganisms present in circulating blood whether continuously, intermittently, or transiently are a threat to every organ in the body. Prevalence and antimicrobial susceptibility of microorganisms vary depending upon the geography and the use of antibiotics. Methods: A cross-sectional study to determine the prevalent organisms causing bloodstream infection was conducted. BACTEC BD 9050 system was used to identify the causative organism, and sub-cultures were done on MacConkey Agar and Blood Agar. Antibiotic susceptibility test (AST) was done using Kirby B Disk diffusion method. Results: A total of 170 patients were enrolled, and blood samples of 53 patients showed growth of organisms. Staphylococcus aureus was the most commonly isolated organism. Most of the Gram-positive cocci (GPC) were susceptible to vancomycin and linezolid. Most of the Gram-negative bacilli (GNB) showed sensitivity to cefoperazone/sulbactam followed by imipenem.