Lack of Effect of Platelet Transfusions and Desmopressin on Intracranial Bleeding in a Patient Receiving Ticagrelor. (15th June 2015)

• Record Type: Journal Article
• Authors: Maillard, Julien; Cartier Faessler, Vanessa; Fontana, Pierre; Bonhomme, Fanny
• Is Part Of: A & A case reports. Volume 4:Number 12(2015)
• Publication Date: 2015-06-15
• Subjects: Anesthesiology -- Periodicals; Anesthesia -- Periodicals; Anesthesiology; Analgesia; Anesthesiology; Periodicals; 617.9605
• DOI: 10.1213/XAA.0000000000000156
• Languages: English
• ISSNs: 2325-7237

Abstract

Abstract : We describe a case of a 67-year-old man who required emergency surgery for acute intracranial bleeding after having received a loading dose of aspirin and ticagrelor for an acute ST-elevation myocardial infarction. Before and during the craniocervical decompression, the assessment of platelet function was performed using the Multiplate® analyzer. Biological evaluation of platelet function was consistent with the clinical impression, suggesting that platelet transfusion and desmopressin administration in the presence of ticagrelor had very little, if any, hemostatic effect.