Regioselective nitration of anilines with Fe(NO3)3·9H2O as a promoter and a nitro source. Issue 21 (10th May 2018)

• Record Type: Journal Article
• Authors: Gao, Yang; Mao, Yuanyou; Zhang, Biwei; Zhan, Yingying; Huo, Yanping
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 21(2018)
• Page Start: 3881
• Page End: 3884
• Publication Date: 2018-05-10
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c8ob00841h
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A novel and efficient ortho -nitration reaction of aniline derivatives using the inexpensive and nontoxic Fe(NO3 )3 ·9H2 O as a promoter and a nitro source has been developed. Abstract : An efficient Fe(NO3 )3 ·9H2 O promoted ortho -nitration reaction of aniline derivatives has been developed. This reaction may go through a nitrogen dioxide radical (NO2 ˙) intermediate, which is generated by the thermal decomposition of iron(iii ) nitrate. The practicality of the present method using nontoxic and inexpensive iron reagents has been shown by the broad substrate scope and applications.