Back Cover: Immunopeptidomic Profiling of HLA‐A2‐Positive Triple Negative Breast Cancer Identifies Potential Immunotherapy Target Antigens. Issue 12 (27th June 2018)

• Record Type: Journal Article
• Authors: Ternette, Nicola; Olde Nordkamp, Marloes J. M.; Müller, Julius; Anderson, Amanda P.; Nicastri, Annalisa; Hill, Adrian V. S.; Kessler, Benedikt M.; Li, Demin
• Other Names: Ternette Nicola guestEditor.; Purcell Anthony W. guestEditor.
• Is Part Of: Proteomics. Volume 18:Issue 12(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-06-27
• Subjects: Proteins -- Separation -- Periodicals; Bioinformatics -- Periodicals; Proteomics -- Periodicals; Genomes -- Periodicals; Molecular genetics -- Periodicals; 572.605
• DOI: 10.1002/pmic.201870106
• Languages: English
• ISSNs: 1615-9853

Abstract

Abstract : DOI:10.1002/pmic.201700465 Immunopeptidomic profiling of biopsies from HLA‐A2‐positive triple negative breast cancer patients identifies a high number of shared tumor‐associated HLA‐A2 peptide antigens. Calculation of the average protein tumor‐associated cohort coverage (aTaCC) shortlists antigens that are presented with higher abundance in tumor tissue than in normal tissue and may prioritize the selection of target antigens for immunotherapy. This is reported in article number1700465 by Ternette et al.