Ruthenium-catalyzed synthesis of arylethyl 1, 3, 5-triazines from arylallyl alcohols and biguanides. Issue 33 (13th August 2018)

• Record Type: Journal Article
• Authors: Zeng, Ming; Xie, Zhong Pao; Cui, Dong-Mei; Zhang, Chen
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 33(2018)
• Page Start: 6140
• Page End: 6145
• Publication Date: 2018-08-13
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c8ob01397g
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : An efficient ruthenium-catalyzed synthesis of alkyl-1, 3, 5-triazines from arylallyl alcohols and biguanides has been developed. The reaction occurred in moderate to good yields and tolerated heterocyclic or aryl allyl alcohols containing functionalities such as alkanes, ethers, and halogens. Abstract : An efficient ruthenium-catalyzed synthesis of alkyl-1, 3, 5-triazies from arylallyl alcohols and biguanides has been developed. The reaction occurred in moderate to good yields and tolerated heterocyclic or aryl allyl alcohols containing functionalities such as alkanes, ethers, and halogens. The reaction proceeds through a one-pot sequence of transfer hydrogenation and condensation steps.