PP.13.19: EVOLUTION OF CAROTID ATHEROSCLEROSIS IN TYPE 2 DIABETES AND HYPERTENSION. (June 2015)

• Record Type: Journal Article
• Authors: Ardeleanu, E.; Lighezan, D.; Lighezan, R.; Deleanu, A.; Gurgus, D.; Popovivi, M.; Nicola, P.; Baaj, S.
• Is Part Of: Journal of hypertension. Volume 33(2015)Supplement 1
• Publication Date: 2015-06
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000468091.10334.61
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: To investigate the relationships between carotid atherosclerosis, evaluated by cIMT and plaques and the presence of diabetes associated or not with hypertension in comparison with a control group. Design and method: A cross sectional study was done between the years 2010 and 2014 on a population of 315 patients with age between 31 and 80 years, 164 patients (52.1%) with diabetes, including 79 (48.2%) hypertensive and a control group of 151 (47.9%). Carotid arteries were exanimated with an ultrasound system Sonoscape SSI 8000 equipped with software that automatically identified the borders of the CCA and calculated cIMT. Results: There were significant differences between the diabetes and control group concerning cIMT, weight, BMI, history of hypertension, blood pressure values, LDL, HDL cholesterol and glucose (p < 0.05 for all comparisons). Mean cIMT and plaques correlated best with age, being 0.72 ± 0.15 mm under 50 years, 0.82 ± 0.35 mm between 50–64 years, 0.92 ± 0.34 mm between 65–74 years and 0.96 ± 0.26 mm over 75 years. Carotid plaques were present in diabetes patients under 50 years at 10.5%, in the 50–64 years group at 16.6%, in the 65–74 years group at 31.1% and over 75 years at 56.6%. cIMT correlated significantly with the duration of diabetes, the presence of microabuminuria and with the association of cardiovascular diseases (p < 0.05). Conclusions: We found a statistical significant association between increased cIMT, plaques, type 2 diabetes mellitus and hypertension. Other factors associated with increased cIMT were age, male gender, low HDL cholesterol, high LDL cholesterol levels, duration of diabetes, presence of microalbuminuria, of coronary heart disease and cerebrovascular disease.