Highly efficient one-step microwave-assisted synthesis of structurally diverse bis-substituted α-amino acid derived diimides. Issue 52 (23rd August 2018)

• Record Type: Journal Article
• Authors: Konopka, Marcin; Markiewicz, Grzegorz; Stefankiewicz, Artur R.
• Is Part Of: RSC advances. Volume 8:Issue 52(2018)
• Page Start: 29840
• Page End: 29846
• Publication Date: 2018-08-23
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c8ra05835k
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : We present a facile and widely applicable microwave-assisted protocol for the synthesis of symmetrical diimides based on three distinct aromatic dianhydrides and five natural amino acids. Abstract : We report herein a facile and widely applicable microwave-assisted protocol for the synthesis of symmetrical diimides based on three structurally distinct aromatic dianhydrides: pyromellitic (PMA), biphenyl-tetracarboxylic acid (BPDA) and benzophenone-tetracarboxylic (BTDA) and five natural amino acids (Phe, Tyr, Ile, Lys, Cys). Fifteen symmetrical diimides with different structural characteristics containing a variety of functional groups can be produced with high yields and on a large scale.