PP.03.18: SEASONAL DIFFERENCES IN CIRCADIAN BLOOD PRESSURE IN PATIENTS WITH WELL-CONTROLLED HYPERTENSION. (June 2015)

• Record Type: Journal Article
• Authors: Volkov, D.; Smirnova, M.I.; Gorbunov, V.M.; Boytsov, S.A.; Loukianov, M.M.; Deev, A.D.; Koscheljaevskaya, J.N.; Belova, E.N.; Kalinina, A.M.; Dolotovskaya, P.V.; Dovgalevskij, P.J.; Furman, N.V.; Puchin'yan, N.F.; Volkov, A.K.
• Is Part Of: Journal of hypertension. Volume 33(2015)Supplement 1
• Publication Date: 2015-06
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000467801.23895.db
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: Blood pressure (BP) levels have tendency to seasonal (winter [W] vs. summer [S]) variability in hypertensive patients but some aspects of this problem are not studied yet. The aim of the study was to compare the circadian BP profile in patients with well-controlled hypertension in W and S. Design and method: We included patients from the general population who visited ambulatory clinics for various reasons. The main inclusion criteria were clinical BP (CBP) less than 140/90 mm Hg and regular antihypertensive therapy (AHT) (2 weeks). The ambulatory BP monitoring (ABPM) was performed with the BPLab device (Nizny Novgorod, Russia) twice in each patient: in W (December-February 2012–2014) and in S (June-August 2012–2014). The interval between ABPMs was 6 months ± 10 days. The selection criteria for ABPM records were the quality adequate for sophisticated analyses: duration > 24 hours, absence of data gaps > 1 hour, > 55 readings per 24 hours. Results: The total number of patients was 272: 55.9% men, mean age 57.3 ± 0.7 (M ± m) years, the average body mass index 28.1 ± 0.3 kg/m 2, CBP at inclusion 128.2 ± 0.9/76.3 ± 0.6 mm Hg. The main results are presented in the Table. The seasonal CBP dynamic was typical. In contrast 24-hour BP (BP24) values were higher in the morning and at night in S. Figure. No caption available. Conclusions: The study demonstrated that the patients with well-controlled hypertension do not need the downward titration of AHT in S. The higher values of BP at night and in the morning may be due to relatively high ambient temperature in S in Saratov and absence of indoor air conditioners.