PP.02.37: LIFESTYLES AND VASCULAR STRUCTURE AND FUNCTION PARAMETERS. MARK STUDY. (June 2015)

• Record Type: Journal Article
• Authors: Garcia-Ortiz, L.; Agudo-Conde, C.; Ramos-Blanes, R.; Recio-Rodríguez, J.; Martí, R.; Rodríguez-Sánchez, E.; Rigó, F.; Frontera, G.; Maderuelo-Fernández, J.; Patino-Alonso, M.; Sánchez-Salgado, B.; Rodriguez-Martín, C.; De Cabo-Laso, A.; Castaño-Sánchez, M.; Gomez-Marcos, M.
• Is Part Of: Journal of hypertension. Volume 33(2015)Supplement 1
• Publication Date: 2015-06
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000467777.50337.a6
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: To analyse the relationships between lifestyles and vascular structure and function parameters in patients with intermediate cardiovascular risk. Design and method: We performed a cross sectional study including 500 subject, aged 30 to 75 years (mean: 60.31 ± 8.44), 54.4% men, without cardiovascular diseases from the MARK study, selected by consecutive sampling from a Spanish health centres. Measurement: Cardio-AnkleVascular Index (CAVI), Ankle-brachial index (ABI) and ba-Pulse Wave velocity (PWV)were measurement by VaSera device (Fukuda Denshi) and by brachial oscillometry (Mobil-O-Graph), Aortic PWV (A-PWV), Augmentation index 75% (AIx75%), Cardiac index(CI)and Reflection coefficient(RC). Lifestyles were measurement by questionnaires of diet (Mediterranean diet and DQI), physical exercise (Minnesota), smoke and alcohol. Results: The CAVI mean was 8.59 ± 1.03, in men 8.62 ± 1.16 and in women 8.55 ± 1.03 (p > 0.05). The 29.3% were less than 8 (normal), the 36.6% were between 8 y 9 (border line) and the 34.1% were equal or higher than 9 (Atherosclerosis probably). ABI mean was 14.7 ± 2.7, baPWV 14.7 ± 2.7, CI 2.2 ± 0.4, AIx75% 26.7 ± 13.8. A-PWV 8.6 ± 1.1 and RC 66.3 ± 8.9. They were smoker 21.4%, heavy drinkers 17.8%, sedentary 24.2% and with unhealthy diet 44.4%. DQI Index was 31 ± 3, Mediterranean diet score 6 ± 2, METS standardized 14 days 3541 ± 3358, alcohol in gr/week 74 ± 107, years of smoking 29 ± 12 and smoking index 26 ± 25. We found positive correlation of years of smoking with the CI (r = 0.145, p = 0.01), A-PWV (r = 0.244, p < 0.01), CAVI (r = 0.170, p < 0.01), and negative with ABI (r = -0.128, p = 0.03). Alcohol consumption was negatively correlated with CI(r = -0.137, p < 0.01), AIx75% (r = -0.100, p = 0.03) and the RC (r = -0.137, p < 0.01). Physical activity correlated only with the ABI (r = 0.123, p = 0.01) and the Mediterranean diet score and DQI with A-PWV (r = 0.119, p = 0.01 y r = 0.096, p = 0.03 respectively). Conclusions: The years of smoking are associated with unfavorable vascular structure and function, while alcohol consumption is associated favorably. Physical activity is associated only with increased ABI, while better food pattern is associated with higher pulse wave velocity.