Prophylactic and early targeted treatment of patent ductus arteriosus. Issue 4 (August 2018)

• Record Type: Journal Article
• Authors: Wyllie, Jonathan P.; Gupta, Samir
• Is Part Of: Seminars in fetal & neonatal medicine. Volume 23:Issue 4(2018)
• Page Start: 250
• Page End: 254
• Publication Date: 2018-08
• Subjects: Preterm -- Patent ductus arteriosus -- Early targeted treatment -- Prophylactic treatment -- Ibuprofen -- Indomethacin; Neonatology -- Periodicals; Newborn infants -- Diseases -- Periodicals; Fetus -- Diseases -- Periodicals; 618.9201
• DOI: 10.1016/j.siny.2018.03.005
• Languages: English
• ISSNs: 1744-165X

Abstract

Abstract: Treatment of a haemodynamically significant patent ductus arteriosus (PDA) in the very preterm infant has been an accepted approach for several decades. However, the rationale for closure of PDA has recently been challenged due to reports of success with conservative approaches and the lack of evidence for longer-term benefits from treatment. In this article, we address an approach to assess treatment of those babies most likely to benefit.