Pulsatile flow through a constricted tube: effect of stenosis morphology on hemodynamic parameters. Issue 7 (19th May 2018)

• Record Type: Journal Article
• Authors: Kelidis, Panagiotis; Konstantinidis, Efstathios
• Is Part Of: Computer methods in biomechanics and biomedical engineering. Volume 21:Issue 7(2018)
• Page Start: 479
• Page End: 487
• Publication Date: 2018-05-19
• Subjects: Atherosclerosis -- atheromatous plaque -- blood flow -- hemodynamics -- shear stress; Biomechanics -- Data processing -- Periodicals; Biomedical engineering -- Periodicals; Biomechanics -- Periodicals; Biomedical Engineering -- methods -- Periodicals; Computing Methodologies -- Periodicals; 612.7
• DOI: 10.1080/10255842.2018.1481505
• Languages: English
• ISSNs: 1025-5842

Abstract

Abstract: In this paper, we investigate pulsatile flow through a constricted tube with the aim of assessing the effect of stenosis morphology on hemodynamic parameters. The fluid-solid interaction of pulsatile flow through a compliant tube with elastic walls was simulated using an arbitrary Lagrangian-Eulerian (ALE) finite-element method. We consider blood flow through various mild stenoses of 25.8% severity in diameter with trapezoidal and bell-like morphologies at a fixed Womersley number of 7.75. The results show that the distribution of the time-averaged wall shear stress (TAWSS), which is the main factor affecting the hemodynamic parameters, strongly depends on the axial stretch of the stenosis; elongation of the stenotic region increases by 41.1% the maximum TAWSS for stenoses of trapezoidal morphology whereas the maximum TAWSS decreases by 14.8% for the corresponding stenoses of bell-like morphology. The present findings indicate that risk factors due to atherosclerosis may vary in a complicated manner as an atheromatous plaque gradually builds up and morphs with time.