Tetrahedral DNAzymes for enhanced intracellular gene-silencing activity. Issue 68 (30th July 2018)
- Record Type:
- Journal Article
- Title:
- Tetrahedral DNAzymes for enhanced intracellular gene-silencing activity. Issue 68 (30th July 2018)
- Main Title:
- Tetrahedral DNAzymes for enhanced intracellular gene-silencing activity
- Authors:
- Thai, Hien Bao Dieu
Levi-Acobas, Fabienne
Yum, Soo-Young
Jang, Goo
Hollenstein, Marcel
Ahn, Dae-Ro - Abstract:
- Abstract : We prepared tetrahedral DNAzymes (TDzs) to overcome potential limitations such as insufficient serum stability and poor cellular uptake of single-stranded DNAzymes (ssDzs). Abstract : We prepared tetrahedral DNAzymes (TDzs) to overcome potential limitations such as insufficient serum stability and poor cellular uptake of single-stranded DNAzymes (ssDzs). TDzs showed enhanced serum stability and higher cellular uptake efficiency compared to those of ssDzs, providing significantly improved intracellular gene-silencing activity to down-regulate the target mRNA level.
- Is Part Of:
- Chemical communications. Volume 54:Issue 68(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 68(2018)
- Issue Display:
- Volume 54, Issue 68 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 68
- Issue Sort Value:
- 2018-0054-0068-0000
- Page Start:
- 9410
- Page End:
- 9413
- Publication Date:
- 2018-07-30
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc05721d ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7144.xml