Stimuli-responsive metal–organic supercontainers as synthetic proton receptors. Issue 30 (17th July 2018)

• Record Type: Journal Article
• Authors: Sun, Cheng-Zhe; Cheng, Li-Ji; Qiao, Yupu; Zhang, Li-Yi; Chen, Zhong-Ning; Dai, Feng-Rong; Lin, Wei; Wang, Zhenqiang
• Is Part Of: Dalton transactions. Volume 47:Issue 30(2018)
• Page Start: 10256
• Page End: 10263
• Publication Date: 2018-07-17
• Subjects: Chemistry, Inorganic -- Periodicals; Chemistry, Physical and theoretical -- Periodicals; Chemistry, Inorganic -- Periodicals; 546.05
• DOI: 10.1039/c8dt01900b
• Languages: English
• ISSNs: 1477-9226

Abstract

Abstract : Functional supercontainers exhibit intriguing H + -dependent fluorescent switching behavior, opening exiting new opportunities for proton modulation in both chemistry and biology. Abstract : We demonstrate a proof-of-concept design of a new platform for proton recognition and modulation. The new proton receptors are derived from a unique class of synthetic supercontainers that exhibit exceptional proton binding capacity (over 50 equiv.) and intriguing proton-dependent fluorescent switching behavior. Experimental and computational studies suggest that the proton-responsive event involves a two-step mechanism pertaining to proton binding by both amino and pyrenyl moieties of the supercontainer constructs. The high proton binding capacity of the supercontainers can be further modulated via small-molecule "regulators" that compete for the proton-binding sites, opening exiting new opportunities for proton manipulation in both chemistry and biology.