The CF3-DAST-induced deacylative trifluoromethylthiolation of cyclic 1, 3-diketones/lactams/lactones and its extension to deacylative pentafluorophenylthiolation. Issue 63 (23rd July 2018)

• Record Type: Journal Article
• Authors: Saidalimu, Ibrayim; Yoshioka, Takuya; Liang, Yumeng; Tokunaga, Etsuko; Shibata, Norio
• Is Part Of: Chemical communications. Volume 54:Issue 63(2018)
• Page Start: 8761
• Page End: 8764
• Publication Date: 2018-07-23
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c8cc05409f
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : CF3 -DAST-induced deacylative trifluoromethylthiolation of cyclic 1, 3-diketones lactams, and lactones that provides cyclic trifluoromethylthioketones, lactams and lactones is reported. Abstract : A trifluoromethyl analogue of diethylaminosulfur trifluoride (CF3 -DAST)-induced deacylative trifluoromethylthiolation of cyclic 1, 3-diketones, lactams, and lactones that provides cyclic α-trifluoromethylthioketones, lactams, and lactones is reported. To the best of our knowledge, this method represents the first example of the trifluoromethylthiolation of lactams. A corresponding deacylative pentafluorophenylthiolation using a pentafluorophenyl analogue of diethylaminosulfur trifluoride (C6 F5 -DAST) was also attempted.