INCREASED EPICARDIAL ADIPOSE TISSUE AND ARTERIAL STIFFNESS, USING CARDIO-ANKLE VASCULAR INDEX IN SLEEP APNOEA. (June 2018)

• Record Type: Journal Article
• Authors: Takahashi, M.; Kasuya, S.; Shiba, T.; Terada, H.; Noro, M.
• Is Part Of: Journal of hypertension. Volume 36(2018)Supplement 1
• Publication Date: 2018-06
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000539217.57781.f8
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: To clarify the relationships between severity of obstructive sleep apnea (OSA) and epicardial adipose tissue (EAT), in addition to discusses for arterial stiffness shown by cardio-ankle vascular index (CAVI). Design and method: Consective 110 Japanese patients with obstructive sleep apnea who had CAVI test and computed tomography (CT) were included in this study. EAT, visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were measured and assessed for severity of OSA. Results: Neither the body mass index nor SAT showed any co-relation with severity of OSA. But there were significant positive co-relation between severity of OSA and VAT or EAT (r = 0.17 p < 0.05, r = 0.18 p < 0.05 respectively). In addition, severity of OSA and EAT were selected as contributing factor for CAVI. Conclusions: These data suggested that OSA could be induced by visceral obesity. OSA could be invasive factor for arterial stiffness. EAT may have increased through visceral obesity, intermitted hypoxia and reoxygenation and increasing afterload such as arterial stiffness shown by CAVI. Suitable diet and sleep apnea treatment could be effective to reduce cardial pericardial fat.