EFFECTS OF AIR POLLUTION IN 24H AMBULATORY BLOOD PRESSURE MONITORING. (June 2018)

• Record Type: Journal Article
• Authors: Bacardit, N. Soldevila; Bargalló, E. Vinyoles; Garces, A. Tobias; Real, J.; Del Val, J.; Banegas, J.; Sierra, A. De La; Muñoz, M.; Verdú, J.; Domingo, M.; Mundet, X.; Cruz, J. De La; Segura, J.; Gorostidi, M.; Riulope, L.
• Is Part Of: Journal of hypertension. Volume 36(2018)Supplement 1
• Publication Date: 2018-06
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000539478.50539.8f
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: INTRODUCTION: Air particulate matters and nitrogen and sulfur dioxide are the most worrying environmental pollutants, with the greatest impact on public health. There are studies that relate atmospheric pollution with the increase in office blood pressure, but there is no study that relates air pollution with 24 h ambulatory blood pressure (ABP). Objective: To know the relationship between ABP and classic atmospheric pollutants (PM10, PM2, 5, NO2 and SO2) and the most recent measurement (ultrafine particles, PUF). Design and method: Observational study of temporary and geographical measures of polluants in individual patients (case-time series design) in centers of Primary Care and Units of Hypertension of a large urban area. Untreated > 18 years hypertensive patients were included, with a first valid ABP monitoring (ABPM) conducted between 2005–2014 and with at least one atmospheric pollution reader at < 3 km of radius of the center where the ABPM was performed. Analysis of regression of temporal series adjusted by individual variables (sociodemographic and risk factors) and ecological (environmental temperature). Results: Sample of 2, 888 hypertensive patients. Mean age of 54.3 (SD 14, 6) years and 50, 1% are women. Body Mass Index (BMI) 28.8 kg/m2 (SD 6.4) and 16.9% of the sample smokes. Baseline 24 h ABPM 128.0 (12.7)/77.4 (9.7) mmHg. For each increase of 10 mg/m3 of PM10 an increase of 1.37 mmHg in 24 h diastolicBP (DBP) and 1.48 mmHg in daytime-DBP was observed, statistically significant. For each increase of 1 mg/m3 of PUF 24 h DBP increases in 1.46 mmHg and daytime-DBP in 1.56 mmHg, statistically significant. The calculation was adjusted by temporal variables of ABPM measures, sociodemographic variables and risk factors, and by environmental temperature. No association was found with any of the two pollutants and nighttime-DBP. No statistical relationship was detected between the PM2.5, NO2 and SO2 pollutants and ABPM, nor between any air pollutants and the office BP. Conclusions: The increase in the atmospheric concentration of PM10 and PUF particles the day prior to ABPM is significantly associated with an increase in 24 h DBP and daytime-DBP.