FMD CASE SERIES FROM AN EASTERN EUROPEAN UNIVERSITY ANGIOGRAPHIC CENTER. (June 2018)

• Record Type: Journal Article
• Authors: Yaneva-Sirakova, T.; Kaneva, R.; Vladimirova, L.; Vassilev, D.
• Is Part Of: Journal of hypertension. Volume 36(2018)Supplement 1
• Publication Date: 2018-06
• Subjects: Hypertension -- Periodicals; Hypertension -- Periodicals; 616.132005
• DOI: 10.1097/01.hjh.0000539553.24028.c3
• Languages: English
• ISSNs: 1473-5598

Abstract

Abstract : Objective: To follow-up patients with angiographically proven fibromuscular dysplasia (FMD). Design and method: Design: These is a case series of 10 Caucasian patients with FMD that are followed from diagnosis and up to the present time. They were diagnosed for one year among the patients who have undergone angiography for other reason. The relative percent of the patients with diagnosed FMD was 0.5% from all who have undergone angiography in University Hospital Alexandrovska. Methods: The mean age at diagnosing FMD was around 60 years and 6 (60%) were females. Full medical history and physical examination were taken, ECG, echocardiography, carotid and renal ultrasound in all, in 9 of the cases coronary and renal angiography, in 8 extra- and intracranial angiography. Results: The clinical presentations were unspecific – only in case there was a clear correlation between poorly controlled arterial hypertension and renal FMD inducing significant renal stenosis. All of the patients with renal FMD had hypertension of various severity. Three of the patients received renal interventions (only one for FMD due to significant stenosis), one – carotid stenting for FMD. One of the patients with coronary angiography had coronary FMD of the LAD. All the others were followed and scheduled for angiography of the other vascular beds at risk. Conclusions: This is the first registry and follow-up of patients with FMD in Bulgaria. Careful screening for subtle symptoms is vital for the early angiographic referral and special treatment if needed. There may be specific local differences in the clinical and angiographic presentation of FMD patients. This is unknown to the moment. The gathered patients through the year prompted the first National FMD Registry and a Nation-wide screening program for FMD.