A novel dual-nano assisted synthesis of symmetrical disulfides from aryl/alkyl halides. Issue 15 (3rd August 2018)

• Record Type: Journal Article
• Authors: Devi, Namita; Hazarika, Sukanya; Gogoi, Prasanta; Barman, Pranjit
• Is Part Of: Synthetic communications. Volume 48:Issue 15(2018)
• Page Start: 1927
• Page End: 1938
• Publication Date: 2018-08-03
• Subjects: Column-free separation -- disulfide -- dual-nano -- green synthesis -- recycle; Organic compounds -- Synthesis -- Periodicals; Chemistry, Organic; Synthesis; 547.205
• DOI: 10.1080/00397911.2018.1466335
• Languages: English
• ISSNs: 0039-7911

Abstract

Abstract: Here, we have reported a novel approach towards dual-nano assisted synthesis of disulfides from coupling of alkyl/aryl halides and sulfur nanoparticles. The indium oxide nanoparticles as catalyst expedite the conversion and sulfur nanoparticle notably enhances the miscibility, providing a faster, high yielding and cost-effective process in ethanol-water system. The method has synthetic advantages in terms of mild reaction framework, catalyst regeneration, and absence of any sulfide or polysulfide linkage as by-product leading to a column free synthesis. A variety of alkyl, aryl and heteroaryl symmetrical disulfides are obtained in good to excellent yields up to exceeding 98%. Graphical Abstract: