Double whammy- acute splenic sequestration crisis in patient with aplastic crisis due to acute parvovirus infection. Issue 3 (3rd July 2017)

• Record Type: Journal Article
• Authors: Minhas, Parminder S.; K. Virdi, Jaspreet; Patel, Rajeshkumar
• Is Part Of: Journal of community hospital internal medicine perspectives. Volume 7:Issue 3(2017)
• Page Start: 194
• Page End: 195
• Publication Date: 2017-07-03
• Subjects: Sickle cell disease -- sickle cell trait -- acute splenic sequestration -- transient aplastic crisis -- parvovirus B19 infection; Internal medicine -- Periodicals; Hospitals -- Periodicals; Hospitals, Community; Internal Medicine; Hospitals; Internal medicine; Periodicals; Periodicals; 610
• DOI: 10.1080/20009666.2017.1340729
• Languages: English
• ISSNs: 2000-9666

Abstract

ABSTRACT: Splenic dysfunction is a major feature of sickle cell disease (SCD) and can manifest as acute splenic sequestration crisis (ASSC), which is the earliest life-threatening complication seen in patients with SCD. Aplastic crisis is another potentially deadly complication of sickle cell disease that develops when erythrocyte production temporarily drops. Infection with parvovirus B-19 frequently causes aplastic crises. These two complications are known to be mutually exclusive due to their classic presentation signs and symptoms but there have been few cases where a patient can have concomitant presentation of both phenomena, which can result in a fatal outcome. These few cases force us to rethink the etiology and subsequent management guidelines of these complications. We present to you a case of an unfortunate 23-year-old female who had both complications occurring at the same time, resulting in death.