The effect of lifestyle modification and glycemic control on the efficiency of sildenafil citrate in patients with erectile dysfunction due to type-2 diabetes mellitus. (2nd October 2015)

• Record Type: Journal Article
• Authors: Kirilmaz, Utku; Guzel, Ozer; Aslan, Yilmaz; Balci, Melih; Tuncel, Altug; Atan, Ali
• Is Part Of: Aging male. Volume 18:Number 4(2015:Dec.)
• Page Start: 244
• Page End: 248
• Publication Date: 2015-10-02
• Subjects: Erectile dysfunction -- glisemic control -- lifestyle modification -- type-2 diabetes mellitus; Aging -- Periodicals; Men -- Periodicals; Gerontology -- Periodicals; Men -- Health and hygiene -- Periodicals; Aging -- periodicals; Geriatric -- periodicals; Men -- periodicals; Aged -- periodicals; Aged, 80 and over -- periodicals; 612.67
• DOI: 10.3109/13685538.2015.1072154
• Languages: English
• ISSNs: 1368-5538

Abstract

Abstract: Objectives : We evaluated the effect of lifestyle modifications and glycemic control on the efficiency of sildenafil citrate in patients with type-2 diabetes (T2DM) and erectile dysfunction (ED). Methods : Eighty-three men with ED due to T2DM were included in the study. The Group 1 ( n = 41) patients received lifestyle modifications (diet and exercise), and medical treatment for intensive glycemic control. In Group 2 ( n = 42), in addition to the intensive glycemic control, the patients were given sildenafil citrate® 100 mg for 2–3 per weeks. The changes in ED were compared between the two groups after three months of treatment. Results : The mean age was 54.9 ± 9.1 (26–75) years. An increase in the IIEF-5 scores was observed in 23 of 41 patients in Group 1 (44.2%) and 29 of 42 in Group 2 (55.8%). When the changes of the IIEF-5 scores were evaluated, the mean increase was 2.5 in Group 1, and 5.0 in Group 2 ( p = 0.012). The mean IIEF changes according to the duration of diabetes were 4.8 in <5 years, 3.6 in 5–10 years and 1.6 in >10 years ( p = 0.021). Conclusions : Glycemic control and lifestyle changes are not solely adequate for a better sexual function in ED due to diabetes, and sildenafil citrate should be used additionally.