A rare cause of chest pain in a cancer patient. Issue 2 (1st January 2016)

• Record Type: Journal Article
• Authors: Welaya, Karim; Yousuf, Kabir; Morales, Maria del Pilar
• Is Part Of: Journal of community hospital internal medicine perspectives. Volume 6:Issue 2(2016)
• Publication Date: 2016-01-01
• Subjects: cancer -- arterial thrombosis -- coronary artery disease; Internal medicine -- Periodicals; Hospitals -- Periodicals; Hospitals, Community; Internal Medicine; Hospitals; Internal medicine; Periodicals; Periodicals; 610
• DOI: 10.3402/jchimp.v6.30827
• Languages: English
• ISSNs: 2000-9666

Abstract

Abstract : It is well known that cancer and hypercoagulability go hand in hand. Most thromboembolism is venous in nature although arterial thrombosis can occur. Arterial thrombosis secondary to malignancy is usually seen in the lower extremities; however, it can also be seen elsewhere. This is a case of bronchogenic carcinoma with no history of typical atherosclerotic risk factors including smoking, diabetes mellitus, hypertension, or hyperlipidemia presented with chest pain and was found to have an acute ST segment elevation myocardial infection. Coronary angiography showed a large thrombus in the left anterior descending artery in the absence of any atherosclerotic lesions. Malignancy is considered to be the major contributing factor for this myocardial infarction in the absence of both atherosclerotic risk factors and atherosclerotic lesions in the coronary angiography. We will focus on the relationship between cancer and thrombosis with special emphasis on arterial thromboembolism with subsequent development of myocardial infarction.