Cover Picture: Transport of Nucleoside Triphosphates into Cells by Artificial Molecular Transporters (Angew. Chem. Int. Ed. 31/2018). Issue 31 (15th May 2018)

• Record Type: Journal Article
• Authors: Zawada, Zbigniew; Tatar, Ameneh; Mocilac, Pavle; Buděšínský, Miloš; Kraus, Tomáš
• Is Part Of: Angewandte Chemie international edition. Volume 57:Issue 31(2018)
• Page Start: 9555
• Page End: 9555
• Publication Date: 2018-05-15
• Subjects: anion transporters -- nucleotide triphosphates -- cell-penetrating peptides -- cyclodextrins -- DNA labelling; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201805221
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract : Transport of nucleoside triphosphates across cell membranes does not proceed under ambient conditions. In their Communication onpage 9891 ff., T. Kraus et al. show rapid and selective transport of various fluorescently labeled nucleoside triphosphates (NTPs) into eukaryotic and prokaryotic cells by artificial transporters. The labeled NTPs, which are instantly released in the intracellular space, can be exploited for tracing metabolic processes such as DNA synthesis in live cells.