Bilateral mammoplasty for cancer: Surgical, oncological and patient-reported outcomes. Issue 1 (January 2017)

• Record Type: Journal Article
• Authors: Di Micco, R.; O'Connell, R.L.; Barry, P.A.; Roche, N.; MacNeill, F.A.; Rusby, J.E.
• Is Part Of: European journal of surgical oncology. Volume 43:Issue 1(2017:Jan.)
• Page Start: 68
• Page End: 75
• Publication Date: 2017-01
• Subjects: Therapeutic mammoplasty -- Breast cancer -- Bilateral breast reduction -- Clavien Dindo classification -- BREAST-Q; Oncology -- Periodicals; Cancer -- Surgery -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- surgery -- Periodicals; Cancer -- Chirurgie -- Périodiques; Cancérologie -- Périodiques; Oncologie; Chirurgie (geneeskunde); Electronic journals; Electronic journals -- Sciences; Electronic journals -- Medicine; Electronic journals; 616.994059005
• DOI: 10.1016/j.ejso.2016.08.013
• Languages: English
• ISSNs: 0748-7983

Abstract

Abstract: Introduction: Bilateral mammoplasty (BM) can optimise oncological safety and aesthetic outcomes in women with large or ptotic breasts whose tumour to breast volume ratio or tumour location pose a challenge to standard breast-conserving therapy (BCT) and for whom mastectomy (with or without reconstruction) may be the only alternative. Methods: We undertook a comprehensive analysis of surgical outcomes (complications according to the Clavien Dindo classification), acute radiation morbidity (Radiation Therapy Oncology Group classification), oncological outcomes, and patient satisfaction (BREAST-Q questionnaire) in women who underwent BM for breast cancer (BC) from June 2009–November 2014. Results: 168 women were included. Median age was 55 years (range:33–84) and median tumour size at imaging 35 mm (range:0–170). Median specimen weight was 242 g (range 39–1824). The wise pattern technique was used in 87.5% of procedures. At least one complication occurred in 68 (40.5%) women, mostly Clavien Dindo grade 1. Grade 3 complications were infrequent (8.9%) but occurred mainly on the therapeutic mammoplasty (TM) side ( p < 0.05). Complications were associated with higher BMI, specimen weight and longer time to radiotherapy ( p < 0.05). Median follow-up was 37 months (range: 13–77). Local recurrence occurred in 3 (1.8%), distant metastases in 5 (3.0%), and 10 (6.0%) women have died. The median score for 'satisfaction with breasts' was 77 (range: 0–100). Conclusions: This study provides concurrent data on surgical, oncological and patient-reported outcomes. It offers evidence that BM is an effective treatment for breast cancer in large- or ptotic-breasted women.