A Bullous Flare of a Hyperkeratotic Affair: A Case Report. Issue 6 (November 2016)

• Record Type: Journal Article
• Authors: Klimas, Natasha; West, Cameron; Tarbox, Michelle
• Is Part Of: Journal of cutaneous medicine and surgery. Volume 20:Issue 6(2016:Nov./Dec.)
• Page Start: 589
• Page End: 591
• Publication Date: 2016-11
• Subjects: Darier's disease -- keratosis follicularis -- bullous disorder; Dermatology -- Periodicals; Skin -- Diseases -- Treatment -- Periodicals; Skin -- Surgery -- Periodicals; Dermatology -- Canada -- Periodicals; Skin -- Diseases -- Treatment -- Canada -- Periodicals; Skin -- Surgery -- Canada -- Periodicals; 616.5005
• DOI: 10.1177/1203475416660295
• Languages: English
• ISSNs: 1203-4754

Abstract

Background: Darier's disease is an autosomal dominant genodermatosis typified by hyperkeratotic papules and plaques in a predominately seborrheic distribution. The vesiculo-bullous variant of Darier's disease is rare. Several previously reported cases have demonstrated clinical and microscopic features resembling familial benign chronic pemphigus or Hailey-Hailey disease. Objectives: The objective of this report is to describe an uncommon presentation of Darier's disease, which has been infrequently described in the literature. Methods: The authors present a case of bullous flare of long-standing Darier's disease. Conclusions: Darier's disease may assume several atypical morphologies, including vesiculo-bullous lesions.