Outcome assessment after hip fracture: is EQ-5D the answer?. Issue 3 (March 2014)

• Record Type: Journal Article
• Authors: Parsons, N.; Griffin, X. L.; Achten, J.; Costa, M. L.
• Is Part Of: Bone & joint research. Volume 3:Issue 3(2014)
• Page Start: 69
• Page End: 75
• Publication Date: 2014-03
• Subjects: EQ-5D; Oxford Hip Score; Fragility Fractures; Proximal Femur -- ICECAP-O -- Outcome assessment; Musculoskeletal system -- Periodicals; 573.705
• DOI: 10.1302/2046-3758.33.2000250
• Languages: English
• ISSNs: 2046-3758

Abstract

Abstract : Objectives: To study the measurement properties of a joint specific patient reported outcome measure, a measure of capability and a general health-related quality of life (HRQOL) tool in a large cohort of patients with a hip fracture. Methods: Responsiveness and associations between the Oxford Hip Score (a hip specific measure: OHS), ICEpop CAPability (a measure of capability in older people: ICECAP-O) and EuroQol EQ-5D (general health-related quality of life measure: EQ-5D) were assessed using data available from two large prospective studies. The three outcome measures were assessed concurrently at a number of fixed follow-up time-points in a consecutive sequence of patients, allowing direct assessment of change from baseline, inter-measure associations and validity using a range of statistical methods. Results: ICECAP-O was not responsive to change. EQ-5D was responsive to change from baseline, with an estimated standardised effect size for the two datasets of 0.676 and 0.644 at six weeks and four weeks respectively; this was almost as responsive to change as OHS (1.14 at four weeks). EQ-5D correlated strongly with OHS; Pearson correlation coefficients were 0.74, 0.77 and 0.70 at baseline, four weeks and four months. EQ-5D is a moderately good predictor of death at 12 months following hip fracture. Furthermore, EQ-5D reported by proxies (relatives and carers) behaves similarly to self-reported scores. Conclusions: Our findings suggest that a general HRQOL tool such as EQ-5D could be used to measure outcome for patients recovering from hip fracture, including those with cognitive impairment. Cite this article: Bone Joint Res 2014;3:69–75.