Life‐threatening or nearly life‐threatening complications in living liver donors. Issue 6 (10th May 2018)

• Record Type: Journal Article
• Authors: Onur, Asim; Akbulut, Sami; Dirican, Abuzer; Isik, Burak; Yilmaz, Sezai
• Is Part Of: Clinical transplantation. Volume 32:Issue 6(2018)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2018-05-10
• Subjects: intraoperative complications -- life‐threatening complications -- living donor hepatectomy -- nearly life‐threatening complications -- postoperative complications; Transplantation of organs, tissues, etc -- Periodicals; 617.95
• DOI: 10.1111/ctr.13262
• Languages: English
• ISSNs: 0902-0063

Abstract

Abstract: Objective: To determine the relationship between a transplant center's experience and life‐threatening or nearly life‐threatening complications during living donor hepatectomy (LDH). Methods: The medical records of 1140 patients who underwent LDH were analyzed. To determine the relationship between life‐threatening complications and a transplant center's experience, the following comparisons between LDH cases were performed: first 100 vs subsequent 100; first 100 vs subsequent 1040; first 200 vs subsequent 940; right hepatectomy vs left hepatectomy; and first 5 years of experience vs subsequent 5 years. Results: A total of 36 life‐threatening or nearly life‐threatening complications developed in 34 of 1140 (2.98%) healthy individuals undergoing LDH. Of these, 5 occurred intraoperatively, 26 within 1 month, and 5 beyond 1 month. The most common complications were biliary problems and postoperative bleeding. None of the donors died at follow‐up. One donor underwent deceased donor liver transplantation (DDLT) for severe hepatic failure. Only 2 comparisons were significantly different with regard to life‐threatening complications: the first 100 vs the subsequent 1040 ( P = .03) and the first 200 vs the subsequent 940 ( P = .01). Conclusion: This study indicates that the incidence of life‐threatening or nearly life‐threatening complications are reduced by increased center experience (>200 LDHs).