Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association. Issue 43 (8th May 2018)
- Record Type:
- Journal Article
- Title:
- Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association. Issue 43 (8th May 2018)
- Main Title:
- Interference of citrate-stabilized gold nanoparticles with β2-microglobulin oligomeric association
- Authors:
- Cantarutti, Cristina
Raj, Gijo
Fogolari, Federico
Giorgetti, Sofia
Corazza, Alessandra
Bellotti, Vittorio
Naumov, Panče
Esposito, Gennaro - Abstract:
- Abstract : Citrate-coated gold nanoparticles interfere with the association equilibria of β2-microglobulin and thus inhibit the early events of fibrillogenesis. Abstract : Protein fibrillation is involved in many serious diseases, and protein oligomers are proved to be precursors of amyloid fibrils. NMR and QCMD experiments allowed us to establish that the interaction between citrate-stabilized gold nanoparticles and a paradigmatic amyloidogenic protein, β2-microglobulin, is able to interfere with protein association into oligomers.
- Is Part Of:
- Chemical communications. Volume 54:Issue 43(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 43(2018)
- Issue Display:
- Volume 54, Issue 43 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 43
- Issue Sort Value:
- 2018-0054-0043-0000
- Page Start:
- 5422
- Page End:
- 5425
- Publication Date:
- 2018-05-08
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc01053f ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6959.xml