An azobenzene-based heteromeric prodrug for hypoxia-activated chemotherapy by regulating subcellular localization. Issue 57 (2nd July 2018)
- Record Type:
- Journal Article
- Title:
- An azobenzene-based heteromeric prodrug for hypoxia-activated chemotherapy by regulating subcellular localization. Issue 57 (2nd July 2018)
- Main Title:
- An azobenzene-based heteromeric prodrug for hypoxia-activated chemotherapy by regulating subcellular localization
- Authors:
- Li, Shiying
Jiang, Xueyan
Zheng, Rongrong
Zuo, Shengjia
Zhao, Linping
Fan, Guiling
Fan, Jinghao
Liao, Yonghua
Yu, Xiyong
Cheng, Hong - Abstract:
- Abstract : An azobenzene-based heteromeric prodrug (hNDP) was prepared for tumor targeted chemotherapy by regulating subcellular localization. Abstract : An azobenzene-based heteromeric prodrug (hNDP) was prepared for targeted chemotherapy against hypoxic tumor. hNDP could divert the parent drug from nucleus to cytoplasm with lower toxicity, while the azoreduction of hNDP in hypoxia would activate the drug with a robust anti-tumor effect by initiating the apoptosis-related biochemical cascades.
- Is Part Of:
- Chemical communications. Volume 54:Issue 57(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 57(2018)
- Issue Display:
- Volume 54, Issue 57 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 57
- Issue Sort Value:
- 2018-0054-0057-0000
- Page Start:
- 7983
- Page End:
- 7986
- Publication Date:
- 2018-07-02
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc03430c ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6951.xml