Energy landscape of polymorphic amyloid generation of β2-microglobulin revealed by calorimetry. Issue 57 (3rd July 2018)
- Record Type:
- Journal Article
- Title:
- Energy landscape of polymorphic amyloid generation of β2-microglobulin revealed by calorimetry. Issue 57 (3rd July 2018)
- Main Title:
- Energy landscape of polymorphic amyloid generation of β2-microglobulin revealed by calorimetry
- Authors:
- Kinoshita, Misaki
Lin, Yuxi
Dai, Itoh
Okumura, Masaki
Markova, Natalia
Ladbury, John E.
Sterpone, Fabio
Lee, Young-Ho - Abstract:
- Abstract : ITC-based energy landscape provides a comprehensive understanding of amyloid aggregation in terms of thermodynamics and kinetics. Abstract : Understanding of amyloid aggregation in terms of thermodynamics and kinetics is still limited. We herein examined the mechanism of β2-microglobulin amyloidogenesis using our unique method of isothermal titration calorimetry-based thermodynamic/kinetic measurements, and revealed the energy landscape of polymorphic amyloidogenesis under biological environment-mimicking conditions including shear forces and crowding effects.
- Is Part Of:
- Chemical communications. Volume 54:Issue 57(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 57(2018)
- Issue Display:
- Volume 54, Issue 57 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 57
- Issue Sort Value:
- 2018-0054-0057-0000
- Page Start:
- 7995
- Page End:
- 7998
- Publication Date:
- 2018-07-03
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc02718h ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6951.xml