Spatially encoded diffusion-ordered NMR spectroscopy of reaction mixtures in organic solvents. Issue 14 (21st June 2018)

• Record Type: Journal Article
• Authors: Hamdoun, Ghanem; Guduff, Ludmilla; van Heijenoort, Carine; Bour, Christophe; Gandon, Vincent; Dumez, Jean-Nicolas
• Is Part Of: Analyst. Volume 143:Issue 14(2018)
• Page Start: 3458
• Page End: 3464
• Publication Date: 2018-06-21
• Subjects: Chemistry, Analytic -- Periodicals; 543
• DOI: 10.1039/c8an00434j
• Languages: English
• ISSNs: 0003-2654

Abstract

Abstract : Using a spatial encoding of the diffusion dimension, DOSY NMR data are acquired in less than one second for reaction mixtures in organic solvents. Abstract : Diffusion-ordered NMR spectroscopy (DOSY) is a powerful method for the analysis of mixtures. Classic DOSY methods require several minutes of acquisition, and we show here that DOSY experiments can be recorded in less than one second for the challenging case of solution mixtures in low-viscosity solvents. The proposed method relies on a spatial encoding of the diffusion dimension, for which convection-compensation and spectral-selection strategies are introduced. The method is illustrated with the analysis of a reaction mixture, and more accurate estimates of the diffusion coefficients are obtained.