Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein–Ru(carbene) adduct. Issue 48 (1st May 2018)
- Record Type:
- Journal Article
- Title:
- Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein–Ru(carbene) adduct. Issue 48 (1st May 2018)
- Main Title:
- Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein–Ru(carbene) adduct
- Authors:
- Sullivan, Matthew P.
Nieuwoudt, Michél K.
Bowmaker, Graham A.
Lam, Nelson Y. S.
Truong, Dianna
Goldstone, David C.
Hartinger, Christian G. - Abstract:
- Abstract : The first crystallographic study of a Ru(carbene)–protein adduct is complemented by EPR spectroscopy showing Ru oxidation upon binding. Abstract : The first X-ray structures of adducts formed between a Ru II (N-heterocyclic carbene)(η 6 - p -cymene) compound and a protein are reported. Coordination to the protein induced the cleavage of the cymene ligand and EPR spectroscopy demonstrated the oxidation of the Ru centre.
- Is Part Of:
- Chemical communications. Volume 54:Issue 48(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 48(2018)
- Issue Display:
- Volume 54, Issue 48 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 48
- Issue Sort Value:
- 2018-0054-0048-0000
- Page Start:
- 6120
- Page End:
- 6123
- Publication Date:
- 2018-05-01
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc02433b ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 6955.xml