Cytidine- and guanosine-based nucleotide–lipids. Issue 26 (22nd June 2018)

• Record Type: Journal Article
• Authors: Alies, Bruno; Ouelhazi, Mohamed A.; Patwa, Amit; Verget, Julien; Navailles, Laurence; Desvergnes, Valérie; Barthélémy, Philippe
• Is Part Of: Organic & biomolecular chemistry. Volume 16:Issue 26(2018)
• Page Start: 4888
• Page End: 4894
• Publication Date: 2018-06-22
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c8ob01023d
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A nucleotide–lipids family featuring the four natural nucleobases was explored through their self-assembly properties. Abstract : Hybrid nucleotide–lipids composed of a lipid covalently attached to purine and pyrimidine nucleobases exhibit supramolecular properties. The novel cytidine and guanosine derivatives are promising bioinspired materials, which can act as supramolecular gelators depending on both the nucleobase and the presence of salts. These supramolecular properties are of broad interest for biomedical applications.