Sleep disturbances as predictors of prolonged exposure therapy effectiveness among veterans with PTSD. (October 2017)

• Record Type: Journal Article
• Authors: Sexton, Minden B.; Avallone, Kimberly M.; Smith, Erin R.; Porter, Katherine E.; Ashrafioun, Lisham; Todd Arnedt, J.; Rauch, Sheila A.M.
• Is Part Of: Psychiatry research. Volume 256(2017)
• Page Start: 118
• Page End: 123
• Publication Date: 2017-10
• Subjects: Sleep -- Prolonged exposure therapy -- Veterans -- Effectiveness -- Posttraumatic stress disorder; Psychiatry -- Periodicals; Psychiatry -- periodicals; Psychiatrie -- Périodiques; 616.89
• DOI: 10.1016/j.psychres.2017.06.044
• Languages: English
• ISSNs: 0165-1781

Abstract

Abstract: Sleep disturbances (SD) are pronounced in Veterans with posttraumatic stress disorder (PTSD). In clinical trials, SD have been shown to limit the effectiveness of evidence-based treatments for non-PTSD disorders. The purpose of this study was to investigate the relationships between pretreatment SD and the effectiveness of Prolonged Exposure (PE) therapy for Veterans with PTSD. Twenty-one Veterans completed the Pittsburgh Sleep Quality Index (PSQI) and the Clinician Administered PTSD Scale upon presenting to a PTSD specialty clinic. Veterans completed the PTSD Symptom Checklist-Civilian (PCL-C) at the initiation of PE and biweekly thereafter for the duration of treatment (96 total assessments). Correlations and hierarchical linear modeling were utilized to examine the potential impact of baseline sleep variables on the slope and magnitude of treatment outcomes. Higher PSQI total scores, and higher sleep latency and sleep medication use subscale scores were associated with higher PCL-C scores at baseline. Veterans evidenced significant reductions in PTSD symptoms during the course of the treatment study. Total PSQI scores and composites were not associated with reduced effectiveness of PE treatment or the slope of PTSD symptom changes. Sleep disturbances do not preclude Veterans from benefits derived from engagement in this gold standard PTSD intervention. Highlights: Pretreatment sleep problems were associated with elevated symptoms of PTSD. Baseline sleep problems did not diminish prolonged exposure therapy effectiveness. Initial sleep disturbances did not reduce the speed of PTSD symptom reduction. Preparatory sleep interventions do not appear warranted to augment EBPs for PTSD.