A case of drug induced lung injury caused by levofloxacin eye drops. (2018)

• Record Type: Journal Article
• Authors: Hosogaya, Naoki; Toida, Kazuhiro; Ishihara, Hiroshi; Kugiyama, Kiyotaka
• Is Part Of: Respiratory medicine case reports. Volume 24(2018)
• Page Start: 12
• Page End: 15
• Publication Date: 2018
• Subjects: Levofloxacin -- Eye drop -- Ophthalmic solution -- Drug-induced lung injury -- Eosinophilic pneumonia; CT computed tomography -- BNP brain natriuretic peptide -- TAZ/PIPC tazobactam/piperacillin -- MEPM meropenem -- BALF bronchoalveolar lavage fluid -- DLST drug lymphocyte stimulation test -- PMDA Pharmaceuticals and Medical Devices Agency -- EP eosinophilic pneumonia; Respiratory organs -- Diseases -- Periodicals; Chest -- Diseases -- Periodicals; Respiratory Tract Diseases -- Periodicals; Respiratory System -- Periodicals; Chest -- Diseases; Respiratory organs -- Diseases; Electronic journals; Periodicals; 616.2
• DOI: 10.1016/j.rmcr.2018.03.010
• Languages: English
• ISSNs: 2213-0071

Abstract

Abstract: A 78 year-old man, who received levofloxacin eye drops as a perioperative prophylactic antibacterial agent for cataract surgery, developed pyrexia and dyspnea, followed by respiratory failure. He was diagnosed as drug-induced lung injury due to levofloxacin, and the symptoms improved after the administration of corticosteroids and discontinuation of levofloxacin eye drops. The incidence of levofloxacin-induced lung injury is rare for its frequent prescription. Moreover, eye drops of it has never been reported to cause lung injury. We should be aware of eye drops as a causative dosage forms of drug-induced lung injury.