Chronic periodontitis is associated with erectile dysfunction. A case–control study in european population. (28th May 2018)

• Record Type: Journal Article
• Authors: Martín, Amada; Bravo, Manuel; Arrabal, Miguel; Magán‐Fernández, Antonio; Mesa, Francisco
• Is Part Of: Journal of clinical periodontology. Volume 45:Number 7(2018)
• Page Start: 791
• Page End: 798
• Publication Date: 2018-05-28
• Subjects: cardiovascular diseases -- case–control studies -- chronic periodontitis -- erectile dysfunction -- periodontics; Periodontics -- Periodicals; 617.6
• DOI: 10.1111/jcpe.12909
• Languages: English
• ISSNs: 0303-6979

Abstract

Abstract: Aim: To determine the association between chronic periodontitis and erectile dysfunction adjusting for biochemical markers and other comorbidities. Methods: A case–control study was conducted on 158 male patients; 80 cases with erectile dysfunction according to the International Index of Erectile Function and 78 controls. Sociodemographic data were gathered, and a periodontal examination was performed. Testosterone, lipid profile, C‐reactive protein and glycaemic parameters were assessed. All variables were compared between groups, and multivariate logistic regression analyses were performed. Results: 74% of the cases were diagnosed with chronic periodontitis. Number of sites with pocket probing depth 4‐6 mm ( p = 0.05) and number of sites with clinical attachment loss >3 mm ( p < 0.01) were higher in the cases. Triglycerides ( p < 0.01), C‐reactive protein ( p = 0.02) and glycosylated haemoglobin ( p = 0.04) were also higher in the cases. Logistic regression showed that patients with chronic periodontitis were more likely to have erectile dysfunction (OR=2.17; 95% CI (1.06–4.43); p = 0.03) independently of other confounders. Conclusion: Patients with erectile dysfunction showed worse periodontal condition. Chronic periodontitis seems to play a key role as a risk factor in the pathogenesis of erectile dysfunction independently of other morbidities.